Police were called to the scene of a single vehicle crash in Hoppers Crossing this afternoon.
It is believed the vehicle, a Subaru Liberty wagon, is stolen and flipped on Old Geelong Road just after 6.30 pm.
There were four occupants. One male and one female were arrested at the scene, one female was transported to the hospital with life-threatening injuries and the male driver initially fled the scene and has since been arrested.
The exact circumstances are being investigated and anyone with dashcam footage or information is urged to contact Crime Stoppers on 1800 333 000.
A series of car thefts has led to many arrests in the Wyndham area lately. Five car thieves were arrested just two days ago and nine were also recently arrested after a series of gym burglaries and car thefts