Police are investigation a collision in Altona on Monday evening, 8 August.
Three cars collided on the Princes Freeway outbound lanes shortly before 7pm.
The incident occurred approximately 300 metres from the Kororoit Creek Road exit.
Two male drivers were taken to the hospital, one with life-threatening injuries and the other with minor injuries.
Two other people were also taken to the hospital for observation and the cause of the collision is under investigation.
The outbound lanes of the freeway have been closed for approximately 2hrs.
Any witnesses or anyone with dashcam footage is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au