Police are appealing for witnesses following a collision on the Princes Freeway, Altona this afternoon.
Investigators understand a small Fuso truck and a white Holden Barina car were travelling city-bound about 3.35pm.
The two vehicles collided between Kororoit Creek Road and Dohertys Road, causing the truck to roll on its side.
Westgate Highway Patrol are investigating if road-rage was a contributing factor.
They are calling for anyone who witnessed the incident or either vehicle prior to the collision, to contact Crime Stoppers.
Police are also seeking dash cam footage of either vehicle.